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NFL Week 5: Odds, Expert Predictions, Top Bets, Spreads, Teasers, Survivor Picks, TV Schedule, Live Streaming, and More

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NFL Week 5 Preview: Key Matchups and Expert Picks

As we dive into Week 5 of the NFL season, the excitement is palpable. This week promises thrilling matchups, including the Cincinnati Bengals aiming to upset Lamar Jackson and the Baltimore Ravens, the Denver Broncos looking to secure back-to-back victories against the Davante Adams-less Las Vegas Raiders, and Justin Fields striving to solidify his position as the Pittsburgh Steelers’ starting quarterback with a prime-time showdown against the Dallas Cowboys. Let’s break down the key games and expert insights for this week.

New York Jets at Minnesota Vikings (London)

Time: Sunday, 9:30 a.m. ET (NFL Network)
Open: Jets -3.5, O/U 44.5

This London matchup features a surprising twist: Sam Darnold, who has emerged as a top quarterback, leads the league in touchdown passes with 11. The Jets boast the second-best pass defense, but their stats may be inflated after facing less formidable opponents. Darnold’s performance will be crucial, especially after taking a beating in Week 4. CBS Sports expert John Breech predicts the Vikings will cover the spread, citing their recent success against the Jets.

Baltimore Ravens at Cincinnati Bengals

Time: Sunday, 1 p.m. ET (CBS)
Open: Bengals -1.5, O/U 46.5

The Bengals face a tough challenge against the Ravens, who have a potent rushing attack led by Lamar Jackson. With the Bengals struggling to stop the run, this matchup could tilt heavily in Baltimore’s favor. Jason La Canfora has made the Ravens -2.5 his best bet, highlighting Jackson’s historical success against Cincinnati’s defense. The Ravens have been strong on the road, making them a formidable opponent for the Bengals.

Buffalo Bills at Houston Texans

Time: Sunday, 1 p.m. ET (CBS)
Open: Texans -1.5, O/U 48

In a clash of quarterbacks, Josh Allen and C.J. Stroud are set to light up the scoreboard. The Bills are looking to bounce back after a tough loss, while the Texans are still finding their footing. SportsLine expert Eric Cohen predicts a high-scoring affair, favoring the Bills to come out on top. With both teams capable of explosive plays, fantasy players should start their stars in this matchup.

Carolina Panthers at Chicago Bears

Time: Sunday, 1 p.m. ET (FOX)
Open: Bears -5.5, O/U 42

The Bears seem to be finding their rhythm, especially with Caleb Williams showing improvement. The Panthers, on the other hand, are struggling defensively, allowing the most points per game in the league. Tyler Sullivan believes the Bears will cover at home, taking advantage of the Panthers’ defensive woes. This game could be a turning point for Chicago if they can capitalize on their offensive momentum.

Cleveland Browns at Washington Commanders

Time: Sunday, 1 p.m. ET (FOX)
Open: Browns -2.5, O/U 43.5

Larry Hartstein sees value in taking the points with the Browns. Despite their offensive struggles, the Commanders’ defense has been inconsistent, giving Cleveland a chance to improve offensively. This matchup could be tightly contested, with both teams looking to establish their identity.

Indianapolis Colts at Jacksonville Jaguars

Time: Sunday, 1 p.m. ET (CBS)
Open: Jaguars -2.5, O/U 47

The Jaguars are desperate for a win, having not triumphed at home since 2014 against the Colts. With uncertainty surrounding the Colts’ quarterback situation, CBS Sports Senior NFL Writer Pete Prisco believes the Jaguars will finally secure their first victory of the season.

Miami Dolphins at New England Patriots

Time: Sunday, 1 p.m. ET (FOX)
Open: Dolphins -3.5, O/U 45

The Dolphins are struggling without Tua Tagovailoa, and the Patriots’ defense could exploit this vulnerability. Jordan Dajani predicts a low-scoring game, favoring the Patriots to take advantage of Miami’s recent struggles. This matchup could be pivotal for both teams as they look to regain momentum.

Arizona Cardinals at San Francisco 49ers

Time: Sunday, 4:05 p.m. ET (FOX)
Open: 49ers -9.5, O/U 47

The 49ers have dominated this series, and with the Cardinals’ recent defensive struggles, Eric Cohen expects another convincing win for San Francisco. The 49ers’ offense has been explosive, and they will look to continue that trend against a struggling Arizona defense.

Las Vegas Raiders at Denver Broncos

Time: Sunday, 4:05 p.m. ET (FOX)
Open: Broncos -1, O/U 41

The Broncos’ defense has been impressive, ranking among the best in the league. With Davante Adams likely sidelined, the Raiders may struggle offensively. Jordan Dajani believes the Broncos will keep their momentum going, making them a solid pick this week.

Green Bay Packers at Los Angeles Rams

Time: Sunday, 4:25 p.m. ET (CBS)
Open: Rams -1.5, O/U 48.5

Jordan Love is starting to find his footing, and the Packers could exploit the Rams’ defensive weaknesses. Tyler Sullivan predicts a strong performance from Green Bay, potentially winning by double digits as they look to establish themselves as contenders.

New York Giants at Seattle Seahawks

Time: Sunday, 4:25 p.m. ET (CBS)
Open: Seahawks -3.5, O/U 43

The Giants are coming off a long rest, while the Seahawks are dealing with injuries on defense. Pete Prisco believes the Giants will cover the spread, making this an intriguing matchup as both teams look to find their offensive rhythm.

Dallas Cowboys at Pittsburgh Steelers

Time: Sunday, 8:20 p.m. ET (NBC)
Open: Cowboys -1.5, O/U 43

R.J. White is leaning towards the Under in this matchup, given both teams’ defensive capabilities. The Cowboys and Steelers are both looking to solidify their playoff positions, making this a must-watch game for fans.

New Orleans Saints at Kansas City Chiefs

Time: Monday, 8:15 p.m. ET (ESPN)
Open: Chiefs -8, O/U 44.5

The Chiefs are looking to remain unbeaten against a struggling Saints team. Danny Vithlani is taking the Under, but the Chiefs are favored to win as they continue their quest for another Super Bowl appearance.

As we gear up for an exciting Week 5, these matchups promise to deliver drama, surprises, and plenty of action. Whether you’re a die-hard fan or a casual observer, there’s something for everyone in this week’s slate of games.

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